A Comparison of Two Stability Proteomics Methods for Drug Target Identification in OnePot 2D Format.

Xu, Yingrong; West, Graham M; Abdelmessih, Mario; Troutman, Matthew D; Everley, Robert A

Xu, Yingrong; West, Graham M; Abdelmessih, Mario; Troutman, Matthew D; Everley, Robert A.

Affiliation

Xu Y; Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.
West GM; Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.
Abdelmessih M; Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.
Troutman MD; Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.
Everley RA; Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.

ACS Chem Biol ; 16(8): 1445-1455, 2021 08 20.

Article in En | MEDLINE | ID: mdl-34374519

Subject(s)

Protein Kinase Inhibitors/pharmacology; Protein Kinases/analysis; Proteome/analysis; Proteomics/methods; Staurosporine/pharmacology; Humans; K562 Cells; Protein Kinases/metabolism; Proteome/metabolism

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Full text: 1 Database: MEDLINE Main subject: Protein Kinases / Staurosporine / Proteome / Proteomics / Protein Kinase Inhibitors Type of study: Diagnostic_studies Limits: Humans Language: En Journal: ACS Chem Biol Year: 2021 Type: Article Affiliation country: United States

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