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A multicenter phase 1/2 study investigating the safety, pharmacokinetics, pharmacodynamics and efficacy of a small molecule antimetabolite, RX-3117, plus nab-paclitaxel in pancreatic adenocarcinoma.
Babiker, Hani; Schlegel, Peter J; Hicks, Lee G; Bullock, Andrea J; Burhani, Nafisa; Mahadevan, Daruka; Elquza, Emad; Borad, Mitesh J; Benaim, Ely; Peterson, Christine; Heaton, Callie; Ocean, Allyson J.
Affiliation
  • Babiker H; Formerly Division of Hematology and Oncology, Department of Medicine, University of Arizona Cancer Center, Currently Division of Hematology and Oncology, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA. Babiker.hani@mayo.edu.
  • Schlegel PJ; Cancer Care Northwest PS, Spokane, WA, USA.
  • Hicks LG; , Baptist Lexington Associates, Lexington, KY, USA.
  • Bullock AJ; Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Burhani N; Joliet Oncology Hematology Associates, Joliet, IL, USA.
  • Mahadevan D; Division of Hematology and Oncology, Department of Medicine, Mays Cancer Center, University of Texas Health, San Antonio, TX, USA.
  • Elquza E; Division of Hematology and Oncology, Department of Medicine, University of California Irvine, Irvine, CA, USA.
  • Borad MJ; Division of Hematology and Oncology, Department of Medicie, Mayo Clinic, Phoenix, AZ, USA.
  • Benaim E; Formerly Rexahn Pharmaceuticals, Rockville, MD, USA.
  • Peterson C; Formerly Rexahn Pharmaceuticals, Rockville, MD, USA.
  • Heaton C; Formerly Rexahn Pharmaceuticals, Rockville, MD, USA.
  • Ocean AJ; Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
Invest New Drugs ; 40(1): 81-90, 2022 02.
Article in En | MEDLINE | ID: mdl-34417914
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Paclitaxel / Albumins Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2022 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Paclitaxel / Albumins Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2022 Type: Article Affiliation country: United States