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Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies.
Phillips, Angela M; Lawrence, Katherine R; Moulana, Alief; Dupic, Thomas; Chang, Jeffrey; Johnson, Milo S; Cvijovic, Ivana; Mora, Thierry; Walczak, Aleksandra M; Desai, Michael M.
Affiliation
  • Phillips AM; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
  • Lawrence KR; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
  • Moulana A; NSF-Simons Center for Mathematical and Statistical Analysis of Biology, Harvard University, Cambridge, United States.
  • Dupic T; Quantitative Biology Initiative, Harvard University, Cambridge, United States.
  • Chang J; Department of Physics, Massachusetts Institute of Technology, Cambridge, United States.
  • Johnson MS; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
  • Cvijovic I; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
  • Mora T; Department of Physics, Harvard University, Cambridge, United States.
  • Walczak AM; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
  • Desai MM; Department of Applied Physics, Stanford University, Stanford, United States.
Elife ; 102021 09 07.
Article in En | MEDLINE | ID: mdl-34491198
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Full text: 1 Database: MEDLINE Main subject: Orthomyxoviridae / Broadly Neutralizing Antibodies / Antibodies, Viral / Antibody Affinity Limits: Animals / Humans Language: En Journal: Elife Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Orthomyxoviridae / Broadly Neutralizing Antibodies / Antibodies, Viral / Antibody Affinity Limits: Animals / Humans Language: En Journal: Elife Year: 2021 Type: Article Affiliation country: United States