In vivo somatic cell base editing and prime editing.

Newby, Gregory A; Liu, David R

In vivo somatic cell base editing and prime editing.

Newby, Gregory A; Liu, David R.

Affiliation

Newby GA; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02142 USA. Electronic address: gnewby@broadinstitute.org.
Liu DR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02142 USA. Electronic address: drliu@fas.harvard.edu.

Mol Ther ; 29(11): 3107-3124, 2021 11 03.

Article in En | MEDLINE | ID: mdl-34509669

Subject(s)

CRISPR-Cas Systems; Gene Editing; Genetic Therapy/methods; Animals; CRISPR-Associated Protein 9/metabolism; DNA Breaks, Double-Stranded; Gene Editing/methods; Gene Rearrangement; Gene Transfer Techniques; Genetic Diseases, Inborn/genetics; Genetic Diseases, Inborn/therapy; Genetic Vectors/genetics; Humans; INDEL Mutation; RNA, Guide, Kinetoplastida

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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / CRISPR-Cas Systems / Gene Editing Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2021 Type: Article

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