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Systems analysis of miRNA biomarkers to inform drug safety.
Schofield, Amy L; Brown, Joseph P; Brown, Jack; Wilczynska, Ania; Bell, Catherine; Glaab, Warren E; Hackl, Matthias; Howell, Lawrence; Lee, Stephen; Dear, James W; Remes, Mika; Reeves, Paul; Zhang, Eunice; Allmer, Jens; Norris, Alan; Falciani, Francesco; Takeshita, Louise Y; Seyed Forootan, Shiva; Sutton, Robert; Park, B Kevin; Goldring, Chris.
Affiliation
  • Schofield AL; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Brown JP; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Brown J; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Wilczynska A; bit.bio, Babraham Research Campus, The Dorothy Hodgkin Building, Cambridge, CB22 3FH, UK.
  • Bell C; CVRM Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Glaab WE; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA, 19486, USA.
  • Hackl M; TAmiRNA GmbH, Leberstrasse 20, 1110, Vienna, Austria.
  • Howell L; GlaxoSmithKline (GSK), Stevenage, Greater Cambridge Area, UK.
  • Lee S; ABHI, 1 Duchess St, 4th Floor, Suite 2, London, W1W 6AN, UK.
  • Dear JW; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
  • Remes M; Genomics EMEA, QIAGEN Aarhus, Prismet, Silkeborgvej 2, 8000, Aarhus C, Denmark.
  • Reeves P; Arcis Biotechnology Limited, Suite S07, Techspace One, Sci-tech Daresbury, Keckwick Lane, Daresbury, Warrington, WA4 4AB, UK.
  • Zhang E; Wolfson Centre for Personalised Medicine, Department of Pharmacology and Therapeutics, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK.
  • Allmer J; Applied Bioinformatics, Bioscience, Wageningen University and Research, Droevendaalsesteeg 4, 6708 PB, Wageningen, The Netherlands.
  • Norris A; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Falciani F; Computational Biology Facility, MerseyBio, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK.
  • Takeshita LY; Computational Biology Facility, MerseyBio, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK.
  • Seyed Forootan S; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Sutton R; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7BE, UK.
  • Park BK; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK.
  • Goldring C; MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, University of Liverpool, Sherrington Buildings, Ashton Street, Liverpool, L69 3GE, UK. chrissy@liv.ac.uk.
Arch Toxicol ; 95(11): 3475-3495, 2021 Nov.
Article in En | MEDLINE | ID: mdl-34510227
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Full text: 1 Database: MEDLINE Main subject: MicroRNAs / Biomarkers, Pharmacological Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: MicroRNAs / Biomarkers, Pharmacological Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: United kingdom