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The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.
Amaya, Maria L; Inguva, Anagha; Pei, Shanshan; Jones, Courtney; Krug, Anna; Ye, Haobin; Minhajuddin, Mohammad; Winters, Amanda; Furtek, Steffanie L; Gamboni, Fabia; Stevens, Brett; D'Alessandro, Angelo; Pollyea, Daniel A; Reigan, Philip; Jordan, Craig T.
Affiliation
  • Amaya ML; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Inguva A; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Pei S; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Jones C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Krug A; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Ye H; Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China.
  • Minhajuddin M; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Winters A; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
  • Furtek SL; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO; and.
  • Gamboni F; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO.
  • Stevens B; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO.
  • Pollyea DA; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
  • Reigan P; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO; and.
  • Jordan CT; Division of Hematology, University of Colorado School of Medicine, Aurora, CO.
Blood ; 139(4): 584-596, 2022 01 27.
Article in En | MEDLINE | ID: mdl-34525179
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Leukemia, Myeloid, Acute / Signal Transduction / Minor Histocompatibility Antigens / Proto-Oncogene Proteins c-myc / Amino Acid Transport System ASC / STAT3 Transcription Factor Limits: Humans Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: Colombia
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Leukemia, Myeloid, Acute / Signal Transduction / Minor Histocompatibility Antigens / Proto-Oncogene Proteins c-myc / Amino Acid Transport System ASC / STAT3 Transcription Factor Limits: Humans Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: Colombia