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IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes.
Blencowe, Montgomery; Furterer, Allison; Wang, Qing; Gao, Fuying; Rosenberger, Madeline; Pei, Lina; Nomoto, Hiroshi; Mawla, Alex M; Huising, Mark O; Coppola, Giovanni; Yang, Xia; Butler, Peter C; Gurlo, Tatyana.
Affiliation
  • Blencowe M; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
  • Furterer A; Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
  • Wang Q; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Gao F; Larry L. Hillblom Islet Research Center, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Rosenberger M; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Pei L; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Nomoto H; Larry L. Hillblom Islet Research Center, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Mawla AM; Larry L. Hillblom Islet Research Center, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Huising MO; Larry L. Hillblom Islet Research Center, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Coppola G; Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, Davis, CA, USA.
  • Yang X; Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, Davis, CA, USA.
  • Butler PC; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
  • Gurlo T; Department of Neurology, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA.
Diabetologia ; 65(1): 173-187, 2022 01.
Article in En | MEDLINE | ID: mdl-34554282

Full text: 1 Database: MEDLINE Main subject: Islets of Langerhans / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Diabetologia Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Main subject: Islets of Langerhans / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Diabetologia Year: 2022 Type: Article Affiliation country: United States