Development and validation of assays for the quantification of ß-D-N<sup>4</sup>-hydroxycytidine in human plasma and ß-D-N<sup>4</sup>-hydroxycytidine-triphosphate in peripheral blood mononuclear cell lysates.

Parsons, Teresa L; Kryszak, Lindsay A; Marzinke, Mark A

Development and validation of assays for the quantification of ß-D-N⁴-hydroxycytidine in human plasma and ß-D-N⁴-hydroxycytidine-triphosphate in peripheral blood mononuclear cell lysates.

Parsons, Teresa L; Kryszak, Lindsay A; Marzinke, Mark A.

Affiliation

Parsons TL; Department of Medicine, Johns Hopkins University, 5200 Eastern Ave, Mason F. Lord Tower, Suite 6000, Baltimore, MD 21224, USA.
Kryszak LA; Department of Medicine, Johns Hopkins University, 5200 Eastern Ave, Mason F. Lord Tower, Suite 6000, Baltimore, MD 21224, USA.
Marzinke MA; Department of Medicine, Johns Hopkins University, 5200 Eastern Ave, Mason F. Lord Tower, Suite 6000, Baltimore, MD 21224, USA; Department of Pathology, Johns Hopkins University, 1800 Orleans St., Sheikh Zayed Tower, Baltimore MD 21287, USA. Electronic address: mmarzin1@jhmi.edu.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1182: 122921, 2021 Oct 01.

Article in En | MEDLINE | ID: mdl-34555541

Subject(s)

Cytidine/analogs & derivatives; Cytidine/blood; Cytidine/chemistry; Humans; Reproducibility of Results

Key words

Antiviral; COVID-19; LC-MS/MS; Molnupiravir; SARS Cov-2; ß-D-N(4)-hydroxycytidine

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Full text: 1 Database: MEDLINE Main subject: Cytidine Type of study: Guideline Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2021 Type: Article Affiliation country: United States

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