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Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial.
Ho, Carolyn Y; Day, Sharlene M; Axelsson, Anna; Russell, Mark W; Zahka, Kenneth; Lever, Harry M; Pereira, Alexandre C; Colan, Steven D; Margossian, Renee; Murphy, Anne M; Canter, Charles; Bach, Richard G; Wheeler, Matthew T; Rossano, Joseph W; Owens, Anjali T; Bundgaard, Henning; Benson, Lee; Mestroni, Luisa; Taylor, Matthew R G; Patel, Amit R; Wilmot, Ivan; Thrush, Philip; Vargas, Jose D; Soslow, Jonathan H; Becker, Jason R; Seidman, Christine E; Lakdawala, Neal K; Cirino, Allison L; Burns, Kristin M; McMurray, John J V; MacRae, Calum A; Solomon, Scott D; Orav, E John; Braunwald, Eugene.
Affiliation
  • Ho CY; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. cho@bwh.harvard.edu.
  • Day SM; University of Michigan, Ann Arbor, MI, USA.
  • Axelsson A; Division of Cardiovascular Medicine Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Russell MW; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
  • Zahka K; University of Michigan, Ann Arbor, MI, USA.
  • Lever HM; Cleveland Clinic Foundation, Cleveland, OH, USA.
  • Pereira AC; Cleveland Clinic Foundation, Cleveland, OH, USA.
  • Colan SD; Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.
  • Margossian R; Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
  • Murphy AM; Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
  • Canter C; Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Bach RG; Washington University School of Medicine, St. Louis, MO, USA.
  • Wheeler MT; Washington University School of Medicine, St. Louis, MO, USA.
  • Rossano JW; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Owens AT; Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Bundgaard H; Division of Cardiovascular Medicine Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Benson L; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
  • Mestroni L; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Taylor MRG; Toronto Hospital for Sick Children, Toronto, ON, Canada.
  • Patel AR; University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Wilmot I; University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Thrush P; Departments of Medicine and Radiology, University of Chicago, Chicago, IL, USA.
  • Vargas JD; Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Soslow JH; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • Becker JR; MedStar Heart and Vascular Institute, Washington, USA.
  • Seidman CE; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Lakdawala NK; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Cirino AL; Division of Cardiology, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA.
  • Burns KM; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
  • McMurray JJV; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • MacRae CA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Orav EJ; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Braunwald E; British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.
Nat Med ; 27(10): 1818-1824, 2021 10.
Article in En | MEDLINE | ID: mdl-34556856
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Full text: 1 Database: MEDLINE Main subject: Cardiomyopathy, Hypertrophic / Valsartan / Heart / Heart Failure Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Cardiomyopathy, Hypertrophic / Valsartan / Heart / Heart Failure Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2021 Type: Article Affiliation country: United States