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A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
McCann, Alex J; Lou, Jieqiong; Moustaqil, Mehdi; Graus, Matthew S; Blum, Ailisa; Fontaine, Frank; Liu, Hui; Luu, Winnie; Rudolffi-Soto, Paulina; Koopman, Peter; Sierecki, Emma; Gambin, Yann; Meunier, Frédéric A; Liu, Zhe; Hinde, Elizabeth; Francois, Mathias.
Affiliation
  • McCann AJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Lou J; School of Physics, Department of Biochemistry and Molecular Biology, Bio21, The University of Melbourne, Melbourne, VIC 3010, Australia.
  • Moustaqil M; EMBL Australia Node in Single Molecule Science and School of Medical Sciences, The University of New South Wales, Sydney, NSW 1466, Australia.
  • Graus MS; The David Richmond Laboratory for Cardio-Vascular Development: gene regulation and editing, The Centenary Institute, Newtown, Sydney, NSW 2006, Australia.
  • Blum A; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Fontaine F; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Liu H; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, United States.
  • Luu W; The David Richmond Laboratory for Cardio-Vascular Development: gene regulation and editing, The Centenary Institute, Newtown, Sydney, NSW 2006, Australia.
  • Rudolffi-Soto P; EMBL Australia Node in Single Molecule Science and School of Medical Sciences, The University of New South Wales, Sydney, NSW 1466, Australia.
  • Koopman P; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Sierecki E; EMBL Australia Node in Single Molecule Science and School of Medical Sciences, The University of New South Wales, Sydney, NSW 1466, Australia.
  • Gambin Y; EMBL Australia Node in Single Molecule Science and School of Medical Sciences, The University of New South Wales, Sydney, NSW 1466, Australia.
  • Meunier FA; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Liu Z; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, United States.
  • Hinde E; School of Physics, Department of Biochemistry and Molecular Biology, Bio21, The University of Melbourne, Melbourne, VIC 3010, Australia.
  • Francois M; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Nucleic Acids Res ; 49(19): 10931-10955, 2021 11 08.
Article in En | MEDLINE | ID: mdl-34570228
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Full text: 1 Database: MEDLINE Main subject: Telangiectasis / Transcription, Genetic / SOXF Transcription Factors / Glomerulonephritis / Hypotrichosis / Lymphedema Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2021 Type: Article Affiliation country: Australia
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Telangiectasis / Transcription, Genetic / SOXF Transcription Factors / Glomerulonephritis / Hypotrichosis / Lymphedema Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2021 Type: Article Affiliation country: Australia