Effects of Radix Polygalae on Cognitive Decline and Depression in Estradiol Depletion Mouse Model of Menopause.

Han, Gaeul; Choi, Junhyuk; Cha, Seung-Yun; Kim, Byung Il; Kho, Hee Kyung; Jang, Maeng-Jin; Kim, Mi Ae; Maeng, Sungho; Hong, Heeok

Han, Gaeul; Choi, Junhyuk; Cha, Seung-Yun; Kim, Byung Il; Kho, Hee Kyung; Jang, Maeng-Jin; Kim, Mi Ae; Maeng, Sungho; Hong, Heeok.

Affiliation

Han G; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Choi J; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Cha SY; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Kim BI; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Kho HK; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Jang MJ; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Kim MA; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Maeng S; Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.
Hong H; Department of Gerontology (AgeTech-Service Convergence Major), Graduate School of East-West Medical Science, Kyung Hee University, Yongin-si 17104, Korea.

Curr Issues Mol Biol ; 43(3): 1669-1684, 2021 Oct 19.

Article in En | MEDLINE | ID: mdl-34698102

Subject(s)

Cognitive Dysfunction/etiology; Cognitive Dysfunction/metabolism; Depression/etiology; Depression/metabolism; Drugs, Chinese Herbal/pharmacology; Estradiol/metabolism; Menopause/drug effects; Menopause/metabolism; Animals; Behavior, Animal; Cognitive Dysfunction/drug therapy; Depression/drug therapy; Disease Models, Animal; Estrous Cycle/drug effects; Estrous Cycle/metabolism; Female; Gene Expression; Gene Expression Regulation/drug effects; Hippocampus/drug effects; Hippocampus/metabolism; Mice; Prefrontal Cortex/drug effects; Prefrontal Cortex/metabolism; Vagina/drug effects; Vagina/metabolism; Vagina/pathology

Key words

VCD; cognition; depression; estrogen; radix polygalae

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Full text: 1 Database: MEDLINE Main subject: Menopause / Drugs, Chinese Herbal / Depression / Estradiol / Cognitive Dysfunction Type of study: Prognostic_studies Limits: Animals Language: En Journal: Curr Issues Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article

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