Competitive dCas9 binding as a mechanism for transcriptional control.

Anderson, Daniel A; Voigt, Christopher A

Anderson, Daniel A; Voigt, Christopher A.

Affiliation

Anderson DA; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Voigt CA; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Mol Syst Biol ; 17(11): e10512, 2021 11.

Article in En | MEDLINE | ID: mdl-34747560

Subject(s)

CRISPR-Cas Systems; RNA, Guide, Kinetoplastida; Binding, Competitive; CRISPR-Cas Systems/genetics; Escherichia coli/genetics; Promoter Regions, Genetic; RNA, Guide, Kinetoplastida/genetics

Key words

CRISPRi; analog circuit; ratio sensing; synthetic biology

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Full text: 1 Database: MEDLINE Main subject: RNA, Guide, Kinetoplastida / CRISPR-Cas Systems Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2021 Type: Article Affiliation country: United States

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