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Pregnane-Oximino-Alkyl-Amino-Ether Compound as a Novel Class of TGR5 Receptor Agonist Exhibiting Antidiabetic and Anti-Dyslipidemic Activities.
Gupta, Jyoti; Singh, Dharmendra P; Verma, Prem C; Rahuja, Neha; Srivastava, Rohit; Ahmad, Ishbal; Jaiswal, Natasha; Kumar, Harish; Gupta, Anand P; Gupta, Varsha; Misra, Anamika; Kushwaha, Hari N; Singh, Bhawani; Singh, Sheo K; Dwivedi, Anil K; Gayen, Jiaur R; Sanyal, Sabyasachi; Srivastava, Arvind K; Pratap, Ram; Tamrakar, Akhilesh K.
Affiliation
  • Gupta J; Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Singh DP; Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Verma PC; Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Rahuja N; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Srivastava R; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Ahmad I; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Jaiswal N; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Kumar H; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Gupta AP; Division of Pharmaceutics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Gupta V; Division of Pharmaceutics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Misra A; Division of Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Kushwaha HN; Division of Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Singh B; Division of Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Singh SK; Division of Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Dwivedi AK; Division of Pharmaceutics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Gayen JR; Division of Pharmaceutics, CSIR-Central Drug Research Institute, Lucknow, India.
  • Sanyal S; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Srivastava AK; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Pratap R; Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
  • Tamrakar AK; Division of Bio-chemistry, CSIR-Central Drug Research Institute, Lucknow, India.
Pharmacology ; 107(1-2): 54-68, 2022.
Article in En | MEDLINE | ID: mdl-34814141
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Full text: 1 Database: MEDLINE Main subject: Pregnanes / Receptors, G-Protein-Coupled / Diabetes Mellitus, Experimental / Dyslipidemias / Hypoglycemic Agents / Hypolipidemic Agents Limits: Animals / Humans / Male Language: En Journal: Pharmacology Year: 2022 Type: Article Affiliation country: India
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pregnanes / Receptors, G-Protein-Coupled / Diabetes Mellitus, Experimental / Dyslipidemias / Hypoglycemic Agents / Hypolipidemic Agents Limits: Animals / Humans / Male Language: En Journal: Pharmacology Year: 2022 Type: Article Affiliation country: India