Testing Hypoxia in Pig Meniscal Culture: Biological Role of the Vascular-Related Factors in the Differentiation and Viability of Neonatal Meniscus.

Canciani, Barbara; Herrera Millar, Valentina Rafaela; Pallaoro, Margherita; Aidos, Lucia; Cirillo, Federica; Anastasia, Luigi; Peretti, Giuseppe Maria; Modina, Silvia Clotilde; Mangiavini, Laura; Di Giancamillo, Alessia

Canciani, Barbara; Herrera Millar, Valentina Rafaela; Pallaoro, Margherita; Aidos, Lucia; Cirillo, Federica; Anastasia, Luigi; Peretti, Giuseppe Maria; Modina, Silvia Clotilde; Mangiavini, Laura; Di Giancamillo, Alessia.

Affiliation

Canciani B; IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Herrera Millar VR; Department of Veterinary Medicine, University of Milan, 26900 Lodi, Italy.
Pallaoro M; Department of Veterinary Medicine, University of Milan, 26900 Lodi, Italy.
Aidos L; Department of Veterinary Medicine, University of Milan, 26900 Lodi, Italy.
Cirillo F; Stem Cells for Tissue Engineering Laboratory, IRCCS Policlinico San Donato, 20097 San Donato Milanese, Italy.
Anastasia L; Stem Cells for Tissue Engineering Laboratory, IRCCS Policlinico San Donato, 20097 San Donato Milanese, Italy.
Peretti GM; Faculty of Medicine and Surgery, Università Vita-Salute San Raffaele, 20132 Milan, Italy.
Modina SC; IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Mangiavini L; Department of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Di Giancamillo A; Department of Veterinary Medicine, University of Milan, 26900 Lodi, Italy.

Int J Mol Sci ; 22(22)2021 Nov 18.

Article in En | MEDLINE | ID: mdl-34830345

Subject(s)

Chondrocytes/drug effects; Fibroblasts/drug effects; Hypoxia/metabolism; Menisci, Tibial/drug effects; Oxygen/pharmacology; Animals; Animals, Newborn; Biomarkers/metabolism; Caspase 3/genetics; Caspase 3/metabolism; Cell Differentiation/drug effects; Chondrocytes/cytology; Chondrocytes/metabolism; Collagen Type I/genetics; Collagen Type I/metabolism; Collagen Type II/genetics; Collagen Type II/metabolism; Endostatins/genetics; Endostatins/metabolism; Fibroblasts/cytology; Fibroblasts/metabolism; Gene Expression; Hypoxia/genetics; Menisci, Tibial/cytology; Menisci, Tibial/metabolism; Platelet Endothelial Cell Adhesion Molecule-1/genetics; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Proliferating Cell Nuclear Antigen/genetics; Proliferating Cell Nuclear Antigen/metabolism; SOX9 Transcription Factor/genetics; SOX9 Transcription Factor/metabolism; Swine; Tissue Culture Techniques

Key words

HIF-1α; differentiation; fibro-chondrocytes; hypoxia; meniscus; pig

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Full text: 1 Database: MEDLINE Main subject: Oxygen / Menisci, Tibial / Chondrocytes / Fibroblasts / Hypoxia Limits: Animals Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: Italy

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