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Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Coupland, Claire E; Andrei, Sebastian A; Ansell, T Bertie; Carrique, Loic; Kumar, Pramod; Sefer, Lea; Schwab, Rebekka A; Byrne, Eamon F X; Pardon, Els; Steyaert, Jan; Magee, Anthony I; Lanyon-Hogg, Thomas; Sansom, Mark S P; Tate, Edward W; Siebold, Christian.
Affiliation
  • Coupland CE; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Andrei SA; Department of Chemistry, Imperial College London, 82 Wood Lane, London W12 0BZ, UK.
  • Ansell TB; Department of Biochemistry, University of Oxford, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Carrique L; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Kumar P; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Sefer L; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Schwab RA; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Byrne EFX; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Pardon E; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium; VIB-VUB Center for Structural Biology, Vlaams Instituut Biotechnologie (VIB), Pleinlaan 2, 1050 Brussels, Belgium.
  • Steyaert J; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium; VIB-VUB Center for Structural Biology, Vlaams Instituut Biotechnologie (VIB), Pleinlaan 2, 1050 Brussels, Belgium.
  • Magee AI; National Heart and Lung Institute, Imperial College London, Exhibition Road, London SW7 2AZ, UK.
  • Lanyon-Hogg T; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
  • Sansom MSP; Department of Biochemistry, University of Oxford, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Tate EW; Department of Chemistry, Imperial College London, 82 Wood Lane, London W12 0BZ, UK. Electronic address: e.tate@imperial.ac.uk.
  • Siebold C; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address: christian@strubi.ox.ac.uk.
Mol Cell ; 81(24): 5025-5038.e10, 2021 12 16.
Article in En | MEDLINE | ID: mdl-34890564
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Full text: 1 Database: MEDLINE Main subject: Acyltransferases / Enzyme Inhibitors / Hedgehog Proteins / Membrane Proteins Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Acyltransferases / Enzyme Inhibitors / Hedgehog Proteins / Membrane Proteins Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United kingdom