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Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors.
Li, Zhi-Ying; Xu, Guang-Sen; Song, Yu-Liang; Li, Xun.
Affiliation
  • Li ZY; Key Laboratory of Chemistry and Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Ji'nan, Shandong 250012, China.
  • Xu GS; Key Laboratory of Chemistry and Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Ji'nan, Shandong 250012, China.
  • Song YL; Key Laboratory of Chemistry and Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Ji'nan, Shandong 250012, China.
  • Li X; Institute of Materia Medica, Shandong Provincial Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong 250117, China; Key Laboratory of Forensic Toxicology, Ministry of Public Security, Beijing 100192, China. Electronic address: lixun@sdfmu.edu.cn.
Bioorg Chem ; 119: 105543, 2022 02.
Article in En | MEDLINE | ID: mdl-34929515
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Full text: 1 Database: MEDLINE Main subject: DNA Topoisomerases, Type II / Acridones / Topoisomerase II Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2022 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: DNA Topoisomerases, Type II / Acridones / Topoisomerase II Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2022 Type: Article Affiliation country: China