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Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood.
Kretzer, Christian; Shkodra, Blerina; Klemm, Paul; Jordan, Paul M; Schröder, Daniel; Cinar, Gizem; Vollrath, Antje; Schubert, Stephanie; Nischang, Ivo; Hoeppener, Stephanie; Stumpf, Steffi; Banoglu, Erden; Gladigau, Frederike; Bilancia, Rossella; Rossi, Antonietta; Eggeling, Christian; Neugebauer, Ute; Schubert, Ulrich S; Werz, Oliver.
Affiliation
  • Kretzer C; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Shkodra B; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Klemm P; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Jordan PM; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Schröder D; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Cinar G; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Vollrath A; Institute of Applied Optics and Biophysics, Friedrich Schiller University Jena, Max-Wien Platz 1, 07743, Jena, Germany.
  • Schubert S; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Nischang I; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Hoeppener S; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Stumpf S; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Banoglu E; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Gladigau F; Department of Pharmaceutical Technology and Biopharmacy, Institute of Pharmacy, Friedrich Schiller University Jena, Lessingstraße 8, 07743, Jena, Germany.
  • Bilancia R; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Rossi A; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Eggeling C; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Neugebauer U; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Schubert US; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Werz O; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
Cell Mol Life Sci ; 79(1): 40, 2021 Dec 31.
Article in En | MEDLINE | ID: mdl-34971430
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Full text: 1 Database: MEDLINE Main subject: Leukotrienes / Leukotriene Antagonists / Nanoparticles Limits: Animals / Female / Humans / Male Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Leukotrienes / Leukotriene Antagonists / Nanoparticles Limits: Animals / Female / Humans / Male Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: Germany