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Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms.
Eldehna, Wagdy M; Taghour, Mohammed S; Al-Warhi, Tarfah; Nocentini, Alessio; Elbadawi, Mostafa M; Mahdy, Hazem A; Abdelrahman, Mohamed A; Alotaibi, Ohoud J; Aljaeed, Nada; Elimam, Diaaeldin M; Afarinkia, Kamyar; Abdel-Aziz, Hatem A; Supuran, Claudiu T.
Affiliation
  • Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Taghour MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • Al-Warhi T; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Nocentini A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
  • Elbadawi MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Mahdy HA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
  • Abdelrahman MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt.
  • Alotaibi OJ; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Aljaeed N; Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Elimam DM; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Afarinkia K; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Abdel-Aziz HA; Institute of Cancer Therapeutics, University of Bradford, Bradford, United Kingdom.
  • Supuran CT; Department of Applied Organic Chemistry, National Research Center, Giza, Egypt.
J Enzyme Inhib Med Chem ; 37(1): 531-541, 2022 Dec.
Article in En | MEDLINE | ID: mdl-34991416
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Full text: 1 Database: MEDLINE Main subject: Carbonic Anhydrase Inhibitors / Carbonic Anhydrases / Coumarins / Thiazolidinediones / Drug Discovery / Carbonic Anhydrase IX Limits: Humans Language: En Journal: J Enzyme Inhib Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Type: Article Affiliation country: Egypt
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Carbonic Anhydrase Inhibitors / Carbonic Anhydrases / Coumarins / Thiazolidinediones / Drug Discovery / Carbonic Anhydrase IX Limits: Humans Language: En Journal: J Enzyme Inhib Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Type: Article Affiliation country: Egypt