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Intestinal commensal microbiota and cytokines regulate Fut2+ Paneth cells for gut defense.
Kamioka, Mariko; Goto, Yoshiyuki; Nakamura, Kiminori; Yokoi, Yuki; Sugimoto, Rina; Ohira, Shuya; Kurashima, Yosuke; Umemoto, Shingo; Sato, Shintaro; Kunisawa, Jun; Takahashi, Yu; Domino, Steven E; Renauld, Jean-Christophe; Nakae, Susumu; Iwakura, Yoichiro; Ernst, Peter B; Ayabe, Tokiyoshi; Kiyono, Hiroshi.
Affiliation
  • Kamioka M; Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Goto Y; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Nakamura K; Department of Medicine, School of Medicine and Chiba University-University of California San Diego Center for Mucosal Immunology, Allergy and Vaccine (CU-UCSD cMAV), University of California, San Diego, CA 92093.
  • Yokoi Y; Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition, Osaka 567-0085, Japan.
  • Sugimoto R; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Ohira S; Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba 260-8673, Japan.
  • Kurashima Y; Department of Cell Biological Science, Graduate School of Life Science, Faculty of Advanced Life Science, Hokkaido University, Hokkaido 001-0021, Japan.
  • Umemoto S; Department of Cell Biological Science, Graduate School of Life Science, Faculty of Advanced Life Science, Hokkaido University, Hokkaido 001-0021, Japan.
  • Sato S; Department of Cell Biological Science, Graduate School of Life Science, Faculty of Advanced Life Science, Hokkaido University, Hokkaido 001-0021, Japan.
  • Kunisawa J; Department of Cell Biological Science, Graduate School of Life Science, Faculty of Advanced Life Science, Hokkaido University, Hokkaido 001-0021, Japan.
  • Takahashi Y; Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Domino SE; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Renauld JC; Department of Medicine, School of Medicine and Chiba University-University of California San Diego Center for Mucosal Immunology, Allergy and Vaccine (CU-UCSD cMAV), University of California, San Diego, CA 92093.
  • Nakae S; Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition, Osaka 567-0085, Japan.
  • Iwakura Y; Department of Innovative Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
  • Ernst PB; Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Ayabe T; Department of Medicine, School of Medicine and Chiba University-University of California San Diego Center for Mucosal Immunology, Allergy and Vaccine (CU-UCSD cMAV), University of California, San Diego, CA 92093.
  • Kiyono H; Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Proc Natl Acad Sci U S A ; 119(3)2022 01 18.
Article in En | MEDLINE | ID: mdl-35027453
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Full text: 1 Database: MEDLINE Main subject: Cytokines / Paneth Cells / Gastrointestinal Microbiome / Fucosyltransferases Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Cytokines / Paneth Cells / Gastrointestinal Microbiome / Fucosyltransferases Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article Affiliation country: Japan