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Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
Nightingale, Katie; Potts, Martin; Hunter, Leah M; Fielding, Ceri A; Zerbe, Cassie M; Fletcher-Etherington, Alice; Nobre, Luis; Wang, Eddie C Y; Strang, Blair L; Houghton, Jack W; Antrobus, Robin; Suarez, Nicolas M; Nichols, Jenna; Davison, Andrew J; Stanton, Richard J; Weekes, Michael P.
Affiliation
  • Nightingale K; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Potts M; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Hunter LM; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Fielding CA; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Zerbe CM; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Fletcher-Etherington A; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Nobre L; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
  • Wang ECY; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Strang BL; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Houghton JW; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Antrobus R; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Suarez NM; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Nichols J; Department of Medicine, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Davison AJ; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
  • Stanton RJ; Institute for Infection and Immunity, University of London, London SW17 0RE, United Kingdom.
  • Weekes MP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Proc Natl Acad Sci U S A ; 119(6)2022 02 08.
Article in En | MEDLINE | ID: mdl-35105802
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Full text: 1 Database: MEDLINE Main subject: Nuclear Proteins / Viral Envelope Proteins / Cytomegalovirus Infections / Cytomegalovirus / Immune Evasion / Proteolysis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Nuclear Proteins / Viral Envelope Proteins / Cytomegalovirus Infections / Cytomegalovirus / Immune Evasion / Proteolysis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article Affiliation country: United kingdom