Acute dose toxicity evaluation of the food supplement calcium 3-hydroxy-3-methylbutyrate (HMB) in female Sprague Dawley rats.

Fuller, John C; Rathmacher, John A

Fuller, John C; Rathmacher, John A.

Affiliation

Fuller JC; Metabolic Technologies, LLC, Missoula, MT, 59802, USA. Electronic address: Fuller@mti-hmb.com.
Rathmacher JA; MTI Biotech, Inc, Ames, IA, 50010, USA; Department of Animal Science, Iowa State University, Ames, IA, 50010, USA.

Regul Toxicol Pharmacol ; 130: 105133, 2022 Apr.

Article in En | MEDLINE | ID: mdl-35122888

Subject(s)

Calcium Compounds/toxicity; Dietary Supplements/toxicity; Administration, Oral; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Rats; Rats, Sprague-Dawley; Solubility; Toxicity Tests

Key words

HMB; Preclinical study; Rodents; Safety

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Full text: 1 Database: MEDLINE Main subject: Calcium Compounds / Dietary Supplements Type of study: Guideline Limits: Animals Language: En Journal: Regul Toxicol Pharmacol Year: 2022 Type: Article

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