Comprehensive radiological features of laryngeal sarcoidosis: cases series and systematic review.
Neuroradiology
; 64(6): 1239-1248, 2022 Jun.
Article
in En
| MEDLINE
| ID: mdl-35246700
ABSTRACT
PURPOSE:
To comprehensively summarize the characteristic radiological findings of laryngeal sarcoidosis.METHODS:
We reviewed patients with laryngeal sarcoidosis who underwent computed tomography (CT) and/or magnetic resonance imaging (MRI) and included 8 cases from 8 publications that were found through a systematic review and 6 cases from our institutions. Two board-certified radiologists reviewed and evaluated the radiological images.RESULTS:
Almost all cases exhibited supraglottic lesions 13/14 (92.9%) and most of them involved aryepiglottic folds (12/13, 92.3%), epiglottis (11/14, 78.6%), and arytenoid region (10/14, 71.4%). Most lesions were bilateral (12/14, 85.7%). All cases showed well-defined margins and a diffuse swelling appearance (14/14, 100%). Non-contrast CT revealed a low density (4/5, 80%). The contrast-enhanced CT showed a slight patchy enhancement predominantly at the margin of the lesion in most cases (12/13, 92.3%). In one case, T2-weighted images showed high signal intensity peripherally and low signal intensity centrally (1/1, 100%). Gadolinium-enhanced MRI showed moderate heterogeneous enhancement predominantly at the margin of the lesion (2/2, 100%). In one case, diffusion-weighted imaging showed intermediate signal intensity; the apparent diffusion coefficient value was 2.4 × 10-3 mm2/s. The larynx was the only region affected by sarcoidosis in 57.1% (8/14) of the cases. Involvement of the neck lymph nodes and distant organs was observed in 4/14 (28.6%) patients, respectively.CONCLUSION:
We summarized the CT and MRI findings of patients with laryngeal sarcoidosis. Knowledge of these characteristics is expected to facilitate prompt diagnosis and appropriate management.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Sarcoidosis
/
Magnetic Resonance Imaging
Type of study:
Diagnostic_studies
/
Observational_studies
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Neuroradiology
Year:
2022
Type:
Article
Affiliation country:
United States