Feasibility of a break-in period of less than 24 hours for urgent start peritoneal dialysis: a multicenter study.
Ren Fail
; 44(1): 450-460, 2022 Dec.
Article
in En
| MEDLINE
| ID: mdl-35272577
ABSTRACT
PURPOSE:
Urgent start peritoneal dialysis (USPD) is an effective therapeutic method for end-stage renal disease (ESRD). However, whether it is safe to initiate peritoneal dialysis (PD) within 24 h unclear. We examined the short-term outcomes of a break-in period (BI) of 24 h for patients undergoing USPD.METHODS:
This real-world, multicenter, retrospective cohort study evaluated USPD patients from five centers from January 2013 to August 2020. Patients were divided into BI ≤ 24 h or BI > 24 h groups. The Primary outcomes included incidence of mechanical and infectious complications. The secondary outcome was technique failure. Moreover, we presented a subgroup analysis for patients who did not receive temporary hemodialysis (HD).RESULTS:
A total of 871 USPD patients were included 470 in the BI ≤ 24 h and 401 in the BI > 24 h groups. Mechanical and infectious complications did not differ between the two groups across the follow-up timepoints (2 weeks, 1 month, 3 months, and 6 months) (p > 0.05). Multiple logistic regression analysis revealed that BI ≤ 24 h was not an independent risk factor for mechanical complications, catheter migration, or infectious complications (p > 0.05). A BI ≤ 24 h was not an independent significant risk factor for technique failure by multivariate Cox regression analysis (p > 0.05). The subgroup analysis of patients who did not receive temporary HD returned the same results.CONCLUSION:
Initiating PD within 24 h of catheter insertion was not associated with increased mechanical complications, infectious complications, or technique failures.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Peritoneal Dialysis
/
Kidney Failure, Chronic
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Ren Fail
Journal subject:
NEFROLOGIA
Year:
2022
Type:
Article
Affiliation country:
China