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Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells.
Ramdas, Baskar; Yuen, Lisa Deng; Palam, Lakshmi Reddy; Patel, Roshini; Pasupuleti, Santhosh Kumar; Jideonwo, Victoria; Zhang, Ji; Maguire, Callista; Wong, Eric; Kanumuri, Rahul; Zhang, Chujing; Sandusky, George; Chan, Rebecca J; Zhang, Chi; Stieglitz, Elliot; Haneline, Laura; Kapur, Reuben.
Affiliation
  • Ramdas B; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: ramdasb@iu.edu.
  • Yuen LD; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Palam LR; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Patel R; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Pasupuleti SK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Jideonwo V; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Zhang J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Maguire C; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Wong E; Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, CA, USA.
  • Kanumuri R; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Zhang C; Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, CA, USA.
  • Sandusky G; Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Chan RJ; Senior Director, Oncology, U.S. Medical Affairs, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, USA.
  • Zhang C; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Stieglitz E; Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
  • Haneline L; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Kapur R; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Microbiology and Immunology, Indiana Univers
Mol Ther ; 30(7): 2505-2521, 2022 07 06.
Article in En | MEDLINE | ID: mdl-35443935
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Full text: 1 Database: MEDLINE Main subject: Thrombocytopenia / Leukemia, Myelomonocytic, Juvenile Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2022 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Thrombocytopenia / Leukemia, Myelomonocytic, Juvenile Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2022 Type: Article