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Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells.
Rosebrock, Daniel; Arora, Sneha; Mutukula, Naresh; Volkman, Rotem; Gralinska, Elzbieta; Balaskas, Anastasios; Aragonés Hernández, Amèlia; Buschow, René; Brändl, Björn; Müller, Franz-Josef; Arndt, Peter F; Vingron, Martin; Elkabetz, Yechiel.
Affiliation
  • Rosebrock D; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Arora S; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Mutukula N; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany.
  • Volkman R; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Gralinska E; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Balaskas A; Institute of Biology, Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Berlin, Germany.
  • Aragonés Hernández A; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Buschow R; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Brändl B; Institute of Chemistry and Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Berlin, Germany.
  • Müller FJ; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Arndt PF; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Vingron M; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany.
  • Elkabetz Y; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Nat Cell Biol ; 24(6): 981-995, 2022 06.
Article in En | MEDLINE | ID: mdl-35697781
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Full text: 1 Database: MEDLINE Main subject: Organoids / Neural Stem Cells Limits: Humans Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Organoids / Neural Stem Cells Limits: Humans Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: Germany