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Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.
Danese, Alberto; Patergnani, Simone; Maresca, Alessandra; Peron, Camille; Raimondi, Andrea; Caporali, Leonardo; Marchi, Saverio; La Morgia, Chiara; Del Dotto, Valentina; Zanna, Claudia; Iannielli, Angelo; Segnali, Alice; Di Meo, Ivano; Cavaliere, Andrea; Lebiedzinska-Arciszewska, Magdalena; Wieckowski, Mariusz R; Martinuzzi, Andrea; Moraes-Filho, Milton N; Salomao, Solange R; Berezovsky, Adriana; Belfort, Rubens; Buser, Christopher; Ross-Cisneros, Fred N; Sadun, Alfredo A; Tacchetti, Carlo; Broccoli, Vania; Giorgi, Carlotta; Tiranti, Valeria; Carelli, Valerio; Pinton, Paolo.
Affiliation
  • Danese A; Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies, University of Ferrara, 44121 Ferrara, Italy.
  • Patergnani S; Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies, University of Ferrara, 44121 Ferrara, Italy.
  • Maresca A; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy.
  • Peron C; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.
  • Raimondi A; Centro Imaging Sperimentale, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), San Raffaele Scientific Institute, via Olgettina 60, 20132 Milan, Italy.
  • Caporali L; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy.
  • Marchi S; Department of Clinical and Molecular Sciences, Polytechnical University of Marche, Ancona, Italy.
  • La Morgia C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Del Dotto V; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy.
  • Zanna C; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Iannielli A; Division of Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), San Raffaele Scientific Institute, via Olgettina 60, 20132 Milan, Italy; National Research Council (CNR), Institute of Neuroscience, Milan, Italy.
  • Segnali A; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.
  • Di Meo I; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.
  • Cavaliere A; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.
  • Lebiedzinska-Arciszewska M; Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
  • Wieckowski MR; Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
  • Martinuzzi A; Scientific Institute, IRCCS E. Medea, Department of Conegliano-Pieve di Soligo, Treviso, Italy.
  • Moraes-Filho MN; Instituto de Olhos de Colatina, Colatina, Espírito Santo, Brazil.
  • Salomao SR; Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, São Paulo, Brazil.
  • Berezovsky A; Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, São Paulo, Brazil.
  • Belfort R; Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, São Paulo, Brazil.
  • Buser C; Oak Crest Institute of Science, Monrovia, CA, USA.
  • Ross-Cisneros FN; Doheny Eye Institute, Los Angeles, CA, USA.
  • Sadun AA; Doheny Eye Institute, Los Angeles, CA, USA; Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Tacchetti C; Centro Imaging Sperimentale, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), San Raffaele Scientific Institute, via Olgettina 60, 20132 Milan, Italy; Dipartimento di Medicina Sperimentale, Università degli Studi di Genova, Genoa, Italy.
  • Broccoli V; Division of Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), San Raffaele Scientific Institute, via Olgettina 60, 20132 Milan, Italy; National Research Council (CNR), Institute of Neuroscience, Milan, Italy.
  • Giorgi C; Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies, University of Ferrara, 44121 Ferrara, Italy.
  • Tiranti V; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy. Electronic address: valeria.tiranti@istituto-besta.it.
  • Carelli V; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy. Electronic address: valerio.carelli@unibo.it.
  • Pinton P; Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies, University of Ferrara, 44121 Ferrara, Italy. Electronic address: paolo.pinton@unife.it.
Cell Rep ; 40(3): 111124, 2022 07 19.
Article in En | MEDLINE | ID: mdl-35858578
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Full text: 1 Database: MEDLINE Main subject: Optic Atrophy, Hereditary, Leber Limits: Humans Language: En Journal: Cell Rep Year: 2022 Type: Article Affiliation country: Italy
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Full text: 1 Database: MEDLINE Main subject: Optic Atrophy, Hereditary, Leber Limits: Humans Language: En Journal: Cell Rep Year: 2022 Type: Article Affiliation country: Italy