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Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanova, Tereza; Urzi, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael.
Affiliation
  • Deng H; Department of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland.
  • Gao Y; Department for BioMedical Research, University of Bern, Bern, Switzerland.
  • Trappetti V; Department of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland.
  • Hertig D; Department for BioMedical Research, University of Bern, Bern, Switzerland.
  • Karatkevich D; Institute of Anatomy, University of Bern, Bern, Switzerland.
  • Losmanova T; Department of Neuroradiology, University of Bern, Bern, Switzerland.
  • Urzi C; Institute of Clinical Chemistry, University Hospital Bern, Bern, Switzerland.
  • Ge H; Department of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland.
  • Geest GA; Department for BioMedical Research, University of Bern, Bern, Switzerland.
  • Bruggmann R; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Djonov V; Institute of Pathology, University of Bern, Bern, Switzerland.
  • Nuoffer JM; Department of Neuroradiology, University of Bern, Bern, Switzerland.
  • Vermathen P; Institute of Clinical Chemistry, University Hospital Bern, Bern, Switzerland.
  • Zamboni N; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Riether C; Department of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland.
  • Ochsenbein A; Department for BioMedical Research, University of Bern, Bern, Switzerland.
  • Peng RW; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Kocher GJ; Interfaculty Bioinformatics Unit, Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
  • Schmid RA; Interfaculty Bioinformatics Unit, Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
  • Dorn P; Institute of Anatomy, University of Bern, Bern, Switzerland.
  • Marti TM; Department of Neuroradiology, University of Bern, Bern, Switzerland.
Cell Mol Life Sci ; 79(8): 445, 2022 Jul 25.
Article in En | MEDLINE | ID: mdl-35877003
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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: Switzerland
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Limits: Animals / Humans Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: Switzerland