Max interacting protein 1 induces IL-17-producing T helper/regulatory T imbalance in osteoarthritis by upregulating tectonic family member 2.

Li, Xin; Xiao, Sheng; Li, Fanling; Fang, Ke; Wen, Jie; Gong, Haoli

Li, Xin; Xiao, Sheng; Li, Fanling; Fang, Ke; Wen, Jie; Gong, Haoli.

Affiliation

Li X; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China. Electronic address: lixin6469@163.com.
Xiao S; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China.
Li F; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China.
Fang K; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China.
Wen J; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China.
Gong H; Department of Orthopaedic, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan 410005, PR China.

Tissue Cell ; 78: 101906, 2022 Oct.

Article in En | MEDLINE | ID: mdl-36049372

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/metabolism; Interleukin-17; Membrane Proteins/metabolism; Osteoarthritis; Tumor Suppressor Proteins/metabolism; Animals; Eosine Yellowish-(YS); Forkhead Transcription Factors/metabolism; Hematoxylin; Interferon-gamma; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism; Receptors, Retinoic Acid/metabolism; STAT3 Transcription Factor/metabolism; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha/metabolism

Key words

CD4(+) T cells; IL-17-producing T helper cells; Max interacting protein 1; Osteoarthritis; Regulatory T cells; Tectonic family member 2

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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis / Interleukin-17 / Tumor Suppressor Proteins / Basic Helix-Loop-Helix Transcription Factors / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Tissue Cell Year: 2022 Type: Article

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