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Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites.
Zou, Roger S; Marin-Gonzalez, Alberto; Liu, Yang; Liu, Hans B; Shen, Leo; Dveirin, Rachel K; Luo, Jay X J; Kalhor, Reza; Ha, Taekjip.
Affiliation
  • Zou RS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Marin-Gonzalez A; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Liu HB; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Shen L; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Dveirin RK; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Luo JXJ; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Kalhor R; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Ha T; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Nat Cell Biol ; 24(9): 1433-1444, 2022 09.
Article in En | MEDLINE | ID: mdl-36064968
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Full text: 1 Database: MEDLINE Main subject: RNA, Guide, Kinetoplastida / CRISPR-Cas Systems Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: RNA, Guide, Kinetoplastida / CRISPR-Cas Systems Language: En Journal: Nat Cell Biol Year: 2022 Type: Article Affiliation country: United States