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Development of non-bias phenotypic drug screening for cardiomyocyte hypertrophy by image segmentation using deep learning.
Komuro, Jin; Tokuoka, Yuta; Seki, Tomohisa; Kusumoto, Dai; Hashimoto, Hisayuki; Katsuki, Toshiomi; Nakamura, Takahiro; Akiba, Yohei; Kuoka, Thukaa; Kimura, Mai; Yamada, Takahiro; Fukuda, Keiichi; Funahashi, Akira; Yuasa, Shinsuke.
Affiliation
  • Komuro J; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: sieg_erringen@yahoo.co.jp.
  • Tokuoka Y; Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi, Kanagawa, 223-8522, Japan. Electronic address: tokuoka@fun.bio.keio.ac.jp.
  • Seki T; Department of Healthcare Information Management, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. Electronic address: tomohisaseki@gmail.com.
  • Kusumoto D; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: d-kusumoto@nifty.com.
  • Hashimoto H; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: hisayuki.hashimoto@keio.jp.
  • Katsuki T; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Department of Cardiology, Saitama Municipal Hospital, 2460 Mimuro, Midori-ku, Saitama-shi, Saitama, Japan. Electronic address: rouninnomi@gmail.com.
  • Nakamura T; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: ta-nakamura11@keio.jp.
  • Akiba Y; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: yohey0814@gmail.com.
  • Kuoka T; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: thukaa.kuoka@gmail.com.
  • Kimura M; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: keyten2003@hotmail.com.
  • Yamada T; Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi, Kanagawa, 223-8522, Japan. Electronic address: yamada@bio.keio.ac.jp.
  • Fukuda K; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: kfukuda@a2.keio.jp.
  • Funahashi A; Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama-shi, Kanagawa, 223-8522, Japan. Electronic address: funa@bio.keio.ac.jp.
  • Yuasa S; Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: yuasa@keio.jp.
Biochem Biophys Res Commun ; 632: 181-188, 2022 12 03.
Article in En | MEDLINE | ID: mdl-36215905
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Full text: 1 Database: MEDLINE Main subject: Cardiomegaly / Drug Evaluation, Preclinical / Deep Learning / Heart Failure Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2022 Type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Cardiomegaly / Drug Evaluation, Preclinical / Deep Learning / Heart Failure Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2022 Type: Article