Your browser doesn't support javascript.
loading
Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease.
Guha, Chandana; Khalid, Rabia; van Zwieten, Anita; Francis, Anna; Hawley, Carmel M; Jauré, Allison; Teixeira-Pinto, Armando; Mallard, Alistair R; Bernier-Jean, Amelie; Johnson, David W; Hahn, Deirdre; Reidlinger, Donna; Pascoe, Elaine M; Ryan, Elizabeth G; Mackie, Fiona; McCarthy, Hugh J; Craig, Jonathan C; Varghese, Julie; Kiriwandeniya, Charani; Howard, Kirsten; Larkins, Nicholas G; Macauley, Luke; Walker, Amanda; Howell, Martin; Irving, Michelle; Caldwell, Patrina H Y; Woodleigh, Reginald; Jesudason, Shilpanjali; Carter, Simon A; Kennedy, Sean E; Alexander, Stephen I; McTaggart, Steven; Wong, Germaine.
Affiliation
  • Guha C; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
  • Khalid R; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • van Zwieten A; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
  • Francis A; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Hawley CM; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
  • Jauré A; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Teixeira-Pinto A; Child and Adolescent Renal Services, Children's Health Queensland Hospital and Health Service, Brisbane, QLD, Australia.
  • Mallard AR; Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia.
  • Bernier-Jean A; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Johnson DW; Translational Research Institute, Brisbane, QLD, Australia.
  • Hahn D; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
  • Reidlinger D; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Pascoe EM; Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia.
  • Ryan EG; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Mackie F; School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, QLD, Australia.
  • McCarthy HJ; CIUSSS du Nord-de-l'Île de Montréal, University of Montréal, Montreal, Canada.
  • Craig JC; Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia.
  • Varghese J; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Kiriwandeniya C; Translational Research Institute, Brisbane, QLD, Australia.
  • Howard K; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Larkins NG; Department of Nephrology, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Macauley L; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Walker A; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Howell M; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Irving M; QCIF Facility for Advanced Bioinformatics, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.
  • Caldwell PHY; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
  • Woodleigh R; Department of Nephrology, Sydney Children's Hospital, Randwick, Sydney, NSW, Australia.
  • Jesudason S; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Carter SA; Department of Nephrology, Sydney Children's Hospital, Randwick, Sydney, NSW, Australia.
  • Kennedy SE; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
  • Alexander SI; College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.
  • McTaggart S; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
  • Wong G; Australasian Kidney Trials Network, The University of Queensland, Brisbane, QLD, Australia.
Pediatr Nephrol ; 38(5): 1577-1590, 2023 05.
Article in En | MEDLINE | ID: mdl-36264432
ABSTRACT

BACKGROUND:

Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD.

METHODS:

The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0-16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization.

RESULTS:

The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1-5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis.

CONCLUSION:

The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. A higher resolution version of the Graphical abstract is available as Supplementary information.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Renal Insufficiency, Chronic / Patient Navigation Type of study: Clinical_trials Limits: Child / Female / Humans / Male Country/Region as subject: Oceania Language: En Journal: Pediatr Nephrol Journal subject: NEFROLOGIA / PEDIATRIA Year: 2023 Type: Article Affiliation country: Australia
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Renal Insufficiency, Chronic / Patient Navigation Type of study: Clinical_trials Limits: Child / Female / Humans / Male Country/Region as subject: Oceania Language: En Journal: Pediatr Nephrol Journal subject: NEFROLOGIA / PEDIATRIA Year: 2023 Type: Article Affiliation country: Australia