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Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
Xie, Xudong; Hu, Liangcong; Mi, Bobin; Xue, Hang; Hu, Yiqiang; Panayi, Adriana C; Endo, Yori; Chen, Lang; Yan, Chenchen; Lin, Ze; Li, Hui; Zhou, Wu; Liu, Guohui.
Affiliation
  • Xie X; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
  • Hu L; Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, 430022, China.
  • Mi B; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
  • Xue H; Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, 430022, China.
  • Hu Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
  • Panayi AC; Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, 430022, China.
  • Endo Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
  • Chen L; Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, 430022, China.
  • Yan C; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
  • Lin Z; Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, 430022, China.
  • Li H; Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02215, USA.
  • Zhou W; Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02215, USA.
  • Liu G; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cell Commun Signal ; 20(1): 165, 2022 10 25.
Article in En | MEDLINE | ID: mdl-36284303
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Full text: 1 Database: MEDLINE Main subject: Bone Resorption / Osteoporosis, Postmenopausal / Metformin Limits: Animals / Female / Humans Language: En Journal: Cell Commun Signal Year: 2022 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Bone Resorption / Osteoporosis, Postmenopausal / Metformin Limits: Animals / Female / Humans Language: En Journal: Cell Commun Signal Year: 2022 Type: Article Affiliation country: China