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Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression.
Luppino, Jennifer M; Field, Andrew; Nguyen, Son C; Park, Daniel S; Shah, Parisha P; Abdill, Richard J; Lan, Yemin; Yunker, Rebecca; Jain, Rajan; Adelman, Karen; Joyce, Eric F.
Affiliation
  • Luppino JM; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Field A; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Nguyen SC; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Park DS; Ludwig Center at Harvard, Boston, Massachusetts, United States of America.
  • Shah PP; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Abdill RJ; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Lan Y; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Yunker R; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Jain R; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Adelman K; Department of Cell and Developmental Biology, Department of Medicine, Institute of Regenerative Medicine, Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Joyce EF; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
PLoS Genet ; 18(11): e1010528, 2022 11.
Article in En | MEDLINE | ID: mdl-36449519
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Full text: 1 Database: MEDLINE Main subject: Chromatin / Chromosomal Proteins, Non-Histone / Gene Expression Regulation / Cell Cycle Proteins Limits: Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Chromatin / Chromosomal Proteins, Non-Histone / Gene Expression Regulation / Cell Cycle Proteins Limits: Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2022 Type: Article Affiliation country: United States