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[Implement of mixed reality navigation based on multimodal imaging in the resection of intracranial eloquent lesions].
Qi, Z Y; Zhang, J S; Xu, X H; Gan, Z C; Xiong, R C; Zhang, S Y; Wang, J Y; Liu, M H; Li, Y; Wang, Q; Li, F Y; Chen, X L.
Affiliation
  • Qi ZY; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Zhang JS; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Xu XH; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Gan ZC; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Xiong RC; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Zhang SY; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Wang JY; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Liu MH; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Li Y; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
  • Wang Q; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Li FY; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
  • Chen XL; Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital, Beijing 100853, China.
Zhonghua Wai Ke Za Zhi ; 60(12): 1100-1107, 2022 Dec 01.
Article in Zh | MEDLINE | ID: mdl-36480878
ABSTRACT

Objective:

To examine the clinical feasibility of mixed reality navigation (MRN) technology based on multimodal imaging for the resection of intracranial eloquent lesions.

Methods:

Fifteen patients with intracranial eloquent lesions admitted to the Department of Neurosurgery, the First Medical Center, People's Liberation Army General Hospital from September 2020 to September 2021 were retrospectively enrolled. There were 7 males and 8 females, aged (50±16) years (range 16 to 70 years). Postoperative pathological diagnosis included meningioma (n=7), metastatic carcinoma (n=3), cavernous hemangioma, glioma, ependymoma, aneurysmal changes and lymphoma (n=1, respectively). The open-source software was used to perform the three-dimensional visualization of preoperative images, and the self-developed MRN system was used to perform the fusion and interaction of multimodal images, so as to formulate the surgical plan and avoid damaging the eloquent white matter fiber tracts. Traditional navigation, intraoperative ultrasound and fluorescein sodium angiography were used to determine the extent of lesion resection. The intraoperative conditions of MRN-assisted surgery were analyzed, and the setup time and localization error of MRN system were measured. The changes of postoperative neurological function were recorded.

Results:

MRN based on multimodal imaging was achieved in all patients. The MRN system setup time (M(IQR)) was 36 (12) minutes (range 20 to 44 minutes), and the localization error was 3.2 (2.0) mm (range 2.6 to 6.7 mm). The reliability of eloquent white matter fiber tracts localization based on MRN was rated as "excellent" in 11 cases, "medium" in 3 cases, and "poor" in 1 case. There were no perioperative death and no new impairment in motor, language, or visual functions after operation. Transient limb numbness occurred in 1 patient after operation, and recovered to the preoperative state in 2 weeks after operation.

Conclusion:

The MRN system based on multimodal imaging can improve the surgical accuracy and safety, and reduce the incidence of iatrogenic neurological dysfunction.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: Augmented Reality Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: Zh Journal: Zhonghua Wai Ke Za Zhi Year: 2022 Type: Article Affiliation country: China

Full text: 1 Database: MEDLINE Main subject: Augmented Reality Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: Zh Journal: Zhonghua Wai Ke Za Zhi Year: 2022 Type: Article Affiliation country: China