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Exploring the genetic architecture of protein secretion in Komagataella phaffii (Pichia pastoris) for biotechnology applications.
Swichkow, Chantle Reiko; Bloom, Joshua S; Kruglyak, Leonid.
Affiliation
  • Swichkow CR; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.
  • Bloom JS; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.
  • Kruglyak L; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, California, United States of America.
PLoS Biol ; 20(12): e3001911, 2022 12.
Article in En | MEDLINE | ID: mdl-36525401
Improvements to the production of proteins in industrial yeast species have largely relied on generating variation in a single genetic background. A new study in PLOS Biology leverages natural genetic variation to identify genes and variants with the potential to improve protein yield.
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Full text: 1 Database: MEDLINE Main subject: Pichia / Saccharomycetales Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Pichia / Saccharomycetales Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: United States