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Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons.
Kumar, Meenakshi Sundaram; Fowler-Magaw, Megan E; Kulick, Daniel; Boopathy, Sivakumar; Gadd, Del Hayden; Rotunno, Melissa; Douthwright, Catherine; Golebiowski, Diane; Yusuf, Issa; Xu, Zuoshang; Brown, Robert H; Sena-Esteves, Miguel; O'Neil, Alison L; Bosco, Daryl A.
Affiliation
  • Kumar MS; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Fowler-Magaw ME; Biochemistry and Molecular Biotechnology Program, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Kulick D; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Boopathy S; Neuroscience Program, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Gadd DH; Department of Biology, Neuroscience and Behavior Program, Wesleyan University, Middletown, CT 06459, USA.
  • Rotunno M; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Douthwright C; Biochemistry and Molecular Biotechnology Program, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Golebiowski D; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Yusuf I; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Xu Z; Biochemistry and Molecular Biotechnology Program, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Brown RH; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Sena-Esteves M; Biochemistry and Molecular Biotechnology Program, Morningside Graduate School of Biomedical Sciences, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • O'Neil AL; Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
  • Bosco DA; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Int J Mol Sci ; 23(24)2022 Dec 16.
Article in En | MEDLINE | ID: mdl-36555655
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Full text: 1 Database: MEDLINE Main subject: Single-Domain Antibodies / Amyotrophic Lateral Sclerosis Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Single-Domain Antibodies / Amyotrophic Lateral Sclerosis Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2022 Type: Article Affiliation country: United States