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Enhancement of chlorhexidine activity against planktonic and biofilm forms of oral streptococci by two Croton spp. essential oils from the Caatinga biome.
Vasconcelos, Brendda Miranda; Pereira, Antônio Mateus Gomes; Coelho, Paulo Adenes Teixeira; Cavalcante, Rafaela Mesquita Bastos; Carneiro-Torres, Daniela Santos; Bandeira, Paulo Nogueira; da Silva, Felipe Ferreira; Rodrigues, Tigressa Helena Soares; Gomes, Geovany Amorim; Carneiro, Victor Alves.
Affiliation
  • Vasconcelos BM; Center of Molecular Bioprospecting and Applied Experimentation (NUBEM), University Center INTA - UNINTA, Sobral, Ceará, Brazil.
  • Pereira AMG; Center of Molecular Bioprospecting and Applied Experimentation (NUBEM), University Center INTA - UNINTA, Sobral, Ceará, Brazil.
  • Coelho PAT; Center of Molecular Bioprospecting and Applied Experimentation (NUBEM), University Center INTA - UNINTA, Sobral, Ceará, Brazil.
  • Cavalcante RMB; Laboratory of Biofilms and Antimicrobial Agents (LaBAM), Federal University of Ceará, Sobral, Brazil.
  • Carneiro-Torres DS; Department of Biological Sciences, Feira de Santana State University, Feira de Santana, Brazil.
  • Bandeira PN; Center of Exact Science and Technology, Vale of Acaraú State University, Sobral, Ceará, Brazil.
  • da Silva FF; Center of Exact Science and Technology, Vale of Acaraú State University, Sobral, Ceará, Brazil.
  • Rodrigues THS; Center of Exact Science and Technology, Vale of Acaraú State University, Sobral, Ceará, Brazil.
  • Gomes GA; Center of Exact Science and Technology, Vale of Acaraú State University, Sobral, Ceará, Brazil.
  • Carneiro VA; Center of Molecular Bioprospecting and Applied Experimentation (NUBEM), University Center INTA - UNINTA, Sobral, Ceará, Brazil.
Biofouling ; : 1-10, 2023 Jan 03.
Article in En | MEDLINE | ID: mdl-36597191
ABSTRACT
This work investigates the ability of two Croton spp. essential oils (EO) to enhance chlorhexidine (CHX) activity against oral streptococci. EO's chemical composition of Croton argyrophyllus and C. pluriglandulosus was determined by GC-MS/FID. The microbial growth kinetics and minimum inhibitory concentration (MIC) of EOs and CHX were determined, followed by their synergism against S. mutans UA159 and ATCC 25175, S. salivarius ATCC 7073 and S. sp. ATCC 15300. The microplate-based method was used to determine the EO/CHX activity against 24-h-old biofilms. The major compounds were α-pinene (54.74%) and bicyclogermacrene (16.08%) for EOAr and 1,8-cineole (17.41%), methyleugenol (16.06%) and elemicin (15.99%) for EOPg. Both EO had MIC around 16,000 µg/mL. EOs/CHX presented a synergistic effect against most strains (FICi from 0.133 to 0.375), and OE/CHX-treated biofilms showed a reduction in biomass and cell viability compared to CHX, only (p < 0.01). Thus, the EOs works as natural adjuvants for CHX.
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Full text: 1 Database: MEDLINE Language: En Journal: Biofouling Journal subject: BIOLOGIA Year: 2023 Type: Article Affiliation country: Brazil
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Database: MEDLINE Language: En Journal: Biofouling Journal subject: BIOLOGIA Year: 2023 Type: Article Affiliation country: Brazil