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Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length.
Teape, Daniella; Peterson, Abigail; Ahsan, Nagib; Ellis, Kimberlyn; Correia, Nicholas; Luo, Ryan; Hegarty, Katy; Yao, Hongwei; Dennery, Phyllis.
Affiliation
  • Teape D; Department of Pediatrics, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
  • Peterson A; Department of Molecular Biology, Cell Biology, and Biochemistry, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
  • Ahsan N; COBRE Center for Cancer Research Development at Rhode Island Hospital, Proteomics Core Facility, Division of Surgical Research, Brown University, Providence, Rhode Island, United States.
  • Ellis K; Department of Molecular Biology, Cell Biology, and Biochemistry, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
  • Correia N; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
  • Luo R; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
  • Hegarty K; Department of Molecular Biology, Cell Biology, and Biochemistry, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
  • Yao H; Department of Molecular Biology, Cell Biology, and Biochemistry, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
  • Dennery P; Department of Molecular Biology, Cell Biology, and Biochemistry, Alpert Medical School, Brown University, Providence, Rhode Island, United States.
Am J Physiol Lung Cell Mol Physiol ; 324(3): L325-L334, 2023 03 01.
Article in En | MEDLINE | ID: mdl-36719084
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Full text: 1 Database: MEDLINE Main subject: Cilia / Hyperoxia Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: BIOLOGIA MOLECULAR / FISIOLOGIA Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Cilia / Hyperoxia Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: BIOLOGIA MOLECULAR / FISIOLOGIA Year: 2023 Type: Article Affiliation country: United States