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Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.
Park, Kwang-Su; Qin, Lihuai; Kabir, Md; Luo, Kaixiu; Dale, Brandon; Zhong, Yue; Kim, Arum; Wang, Gang Greg; Kaniskan, Husnu Ümit; Jin, Jian.
Affiliation
  • Park KS; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Qin L; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Kabir M; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Luo K; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Dale B; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhong Y; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Kim A; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
  • Wang GG; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
  • Kaniskan HÜ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
  • Jin J; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
Adv Sci (Weinh) ; 10(10): e2205573, 2023 04.
Article in En | MEDLINE | ID: mdl-36737841

Full text: 1 Database: MEDLINE Main subject: Histones / Polycomb Repressive Complex 1 Limits: Animals / Humans Language: En Journal: Adv Sci (Weinh) Year: 2023 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Main subject: Histones / Polycomb Repressive Complex 1 Limits: Animals / Humans Language: En Journal: Adv Sci (Weinh) Year: 2023 Type: Article Affiliation country: United States