Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors.

Korff, Marvin; Chaudhary, Ahmad; Li, Yinlong; Zhou, Xin; Zhao, Chunyu; Rong, Jian; Chen, Jiahui; Xiao, Zhiwei; Elghazawy, Nehal H; Sippl, Wolfgang; Davenport, April T; Daunais, James B; Wang, Lu; Abate, Carmen; Ahmed, Hazem; Crowe, Ron; Liang, Steven H; Ametamey, Simon M; Wünsch, Bernhard; Haider, Ahmed

Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[¹⁸F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors.

Korff, Marvin; Chaudhary, Ahmad; Li, Yinlong; Zhou, Xin; Zhao, Chunyu; Rong, Jian; Chen, Jiahui; Xiao, Zhiwei; Elghazawy, Nehal H; Sippl, Wolfgang; Davenport, April T; Daunais, James B; Wang, Lu; Abate, Carmen; Ahmed, Hazem; Crowe, Ron; Liang, Steven H; Ametamey, Simon M; Wünsch, Bernhard; Haider, Ahmed.

Affiliation

Korff M; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Chaudhary A; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Li Y; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Zhou X; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Zhao C; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Rong J; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Chen J; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Xiao Z; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Elghazawy NH; Institute of Pharmacy, Department of Medicinal Chemistry, Martin-Luther-University Halle-Wittenberg, W.-Langenbeck-Str. 4, 06120 Halle, Germany.
Sippl W; Institute of Pharmacy, Department of Medicinal Chemistry, Martin-Luther-University Halle-Wittenberg, W.-Langenbeck-Str. 4, 06120 Halle, Germany.
Davenport AT; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Daunais JB; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.
Wang L; Center of Cyclotron and PET Radiopharmaceuticals, Department of Nuclear Medicine and PET/CT-MRI Center, the First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Abate C; Dipartimento di Farmacia-Scienze Del Farmaco, Università Degli Studi di Bari ALDO MORO, Via Orabona 4, Bari 70125, Italy.
Ahmed H; Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Institute of Pharmaceutical Sciences ETH, Vladimir-Prelog-Weg 4, 8093 Zurich, Switzerland.
Crowe R; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Liang SH; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA 30322, USA.
Ametamey SM; Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Institute of Pharmaceutical Sciences ETH, Vladimir-Prelog-Weg 4, 8093 Zurich, Switzerland.
Wünsch B; Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.
Haider A; Department of Radiology, Division of Nuclear Medicine and Molecular Imaging Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.