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Imidazo[1,2-a]Pyridine Derivatives as Novel Dual-Target Inhibitors of ABCB1 and ABCG2 for Reversing Multidrug Resistance.
Li, Hui; Zhang, Sheng-Lie; Jia, Yan-Han; Li, Qian; Feng, Zi-Wen; Zhang, Shi-Duo; Zheng, Wei; Zhou, Ye-Ling; Li, Lin-Lin; Liu, Xue-Chun; Chen, Ya-Qiong; Peng, Hui; You, Qi-Dong; Xu, Xiao-Li.
Affiliation
  • Li H; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Zhang SL; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Jia YH; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Li Q; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Feng ZW; Department of Operational Medicine, Tianjin Institute of Environmental & Operational Medicine, Tianjin 300050, China.
  • Zhang SD; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Zheng W; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Zhou YL; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Li LL; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Liu XC; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • Chen YQ; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Peng H; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
  • You QD; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Xu XL; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.
J Med Chem ; 66(4): 2804-2831, 2023 02 23.
Article in En | MEDLINE | ID: mdl-36780419
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Full text: 1 Database: MEDLINE Main subject: Drug Resistance, Multiple / Drug Resistance, Neoplasm / ATP Binding Cassette Transporter, Subfamily B, Member 2 / Neoplasm Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Drug Resistance, Multiple / Drug Resistance, Neoplasm / ATP Binding Cassette Transporter, Subfamily B, Member 2 / Neoplasm Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Type: Article Affiliation country: China