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A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development.
Chipangura, John K; Ntamo, Yonela; Mohr, Bert; Chellan, Nireshni.
Affiliation
  • Chipangura JK; Faculty of Health Science, University of Cape Town Research Animal Facility, South Africa.
  • Ntamo Y; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa.
  • Mohr B; Faculty of Health Science, University of Cape Town Research Animal Facility, South Africa.
  • Chellan N; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa.
Hum Exp Toxicol ; 42: 9603271221147884, 2023.
Article in En | MEDLINE | ID: mdl-36879529
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Full text: 1 Database: MEDLINE Main subject: Chemical and Drug Induced Liver Injury / Cell Culture Techniques, Three Dimensional Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Hum Exp Toxicol Journal subject: TOXICOLOGIA Year: 2023 Type: Article Affiliation country: South Africa
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Full text: 1 Database: MEDLINE Main subject: Chemical and Drug Induced Liver Injury / Cell Culture Techniques, Three Dimensional Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Hum Exp Toxicol Journal subject: TOXICOLOGIA Year: 2023 Type: Article Affiliation country: South Africa