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Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS.
Parameswaran, Janani; Zhang, Nancy; Braems, Elke; Tilahun, Kedamawit; Pant, Devesh C; Yin, Keena; Asress, Seneshaw; Heeren, Kara; Banerjee, Anwesha; Davis, Emma; Schwartz, Samantha L; Conn, Graeme L; Bassell, Gary J; Van Den Bosch, Ludo; Jiang, Jie.
Affiliation
  • Parameswaran J; Department of Cell Biology, Emory University, Atlanta, United States.
  • Zhang N; Department of Cell Biology, Emory University, Atlanta, United States.
  • Braems E; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Tilahun K; Center for Brain & Disease Research, Laboratory of Neurobiology, VIB, Campus Gasthuisberg, Leuven, Belgium.
  • Pant DC; Department of Cell Biology, Emory University, Atlanta, United States.
  • Yin K; Department of Cell Biology, Emory University, Atlanta, United States.
  • Asress S; Department of Cell Biology, Emory University, Atlanta, United States.
  • Heeren K; Department of Neurology, Emory University, Atlanta, United States.
  • Banerjee A; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Davis E; Center for Brain & Disease Research, Laboratory of Neurobiology, VIB, Campus Gasthuisberg, Leuven, Belgium.
  • Schwartz SL; Department of Cell Biology, Emory University, Atlanta, United States.
  • Conn GL; Department of Cell Biology, Emory University, Atlanta, United States.
  • Bassell GJ; Department of Biochemistry, Emory University, Atlanta, United States.
  • Van Den Bosch L; Department of Biochemistry, Emory University, Atlanta, United States.
  • Jiang J; Department of Cell Biology, Emory University, Atlanta, United States.
Elife ; 122023 04 19.
Article in En | MEDLINE | ID: mdl-37073950
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Full text: 1 Database: MEDLINE Main subject: Frontotemporal Dementia / Amyotrophic Lateral Sclerosis Limits: Animals Language: En Journal: Elife Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Frontotemporal Dementia / Amyotrophic Lateral Sclerosis Limits: Animals Language: En Journal: Elife Year: 2023 Type: Article Affiliation country: United States