S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced expression of matrix metalloproteinase-1 through inhibition of tumor necrosis factor-&#945; converting enzyme-epidermal growth factor receptor axis in human gingival fibroblasts.

Nango, Hiroshi; Ohtani, Masahiro

S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced expression of matrix metalloproteinase-1 through inhibition of tumor necrosis factor-α converting enzyme-epidermal growth factor receptor axis in human gingival fibroblasts.

Nango, Hiroshi; Ohtani, Masahiro.

Affiliation

Nango H; Central Research Institute, Wakunaga Pharmaceutical Co., Ltd., Akitakata, Hiroshima, Japan.
Ohtani M; Central Research Institute, Wakunaga Pharmaceutical Co., Ltd., Akitakata, Hiroshima, Japan.

PLoS One ; 18(4): e0284713, 2023.

Article in En | MEDLINE | ID: mdl-37083725

Subject(s)

Lipopolysaccharides; Matrix Metalloproteinase 1; Humans; ADAM17 Protein/metabolism; Cells, Cultured; ErbB Receptors/metabolism; Fibroblasts/metabolism; Gingiva; Lipopolysaccharides/pharmacology; Lipopolysaccharides/metabolism; Matrix Metalloproteinase 1/metabolism; Matrix Metalloproteinase 3/metabolism; Tumor Necrosis Factor-alpha/metabolism; Garlic; Plant Extracts

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Full text: 1 Database: MEDLINE Main subject: Lipopolysaccharides / Matrix Metalloproteinase 1 Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2023 Type: Article Affiliation country: Japan

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