CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from <i>Aspergillus nidulans</i> reveals key conformations for activity regulation and function.

Han, Xu; D'Angelo, Cecilia; Otamendi, Ainara; Cifuente, Javier O; de Astigarraga, Elisa; Ochoa-Lizarralde, Borja; Grininger, Martin; Routier, Francoise H; Guerin, Marcelo E; Fuehring, Jana; Etxebeste, Oier; Connell, Sean R

CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function.

Han, Xu; D'Angelo, Cecilia; Otamendi, Ainara; Cifuente, Javier O; de Astigarraga, Elisa; Ochoa-Lizarralde, Borja; Grininger, Martin; Routier, Francoise H; Guerin, Marcelo E; Fuehring, Jana; Etxebeste, Oier; Connell, Sean R.

Affiliation

Han X; Structural Biology of Cellular Machines Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital , Barakaldo, Bizkaia, Spain.
D'Angelo C; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) , Derio, Spain.
Otamendi A; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) , Derio, Spain.
Cifuente JO; Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital , Barakaldo, Bizkaia, Spain.
de Astigarraga E; Laboratory of Biology, Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country, UPV/EHU , San Sebastian, Spain.
Ochoa-Lizarralde B; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) , Derio, Spain.
Grininger M; Structural Glycobiology Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital , Barakaldo, Bizkaia, Spain.
Routier FH; Structural Biology of Cellular Machines Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital , Barakaldo, Bizkaia, Spain.
Guerin ME; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) , Derio, Spain.
Fuehring J; Structural Biology of Cellular Machines Laboratory, Biocruces Bizkaia Health Research Institute, Cruces University Hospital , Barakaldo, Bizkaia, Spain.
Etxebeste O; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA) , Derio, Spain.
Connell SR; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt , Frankfurt am Main, Germany.