Acute Portal Vein Thrombosis as an Initial Presentation of Protein C Deficiency: A Case Report.
Cureus
; 15(6): e40407, 2023 Jun.
Article
in En
| MEDLINE
| ID: mdl-37456450
ABSTRACT
Protein C (PC) is an essential vitamin K-dependent protein that regulates thrombosis and hemostasis in the body. A mutation in the PROC gene on chromosome 2q14.3 results in PC deficiency. The clinical presentation of PC deficiency can vary, ranging from a single vein thrombosis to disseminated intravascular coagulation, purpura fulminans, or even life-threatening complications such as sepsis. Here, we present a case of a 37-year-old female who was found to have acute portal vein thrombosis as an initial presentation of PC deficiency. She presented to the hospital with acute onset of abdominal pain associated with nausea, blood-streaked emesis, and bloody bowel movement.
Full text:
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Database:
MEDLINE
Language:
En
Journal:
Cureus
Year:
2023
Type:
Article
Affiliation country:
United States