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Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases.
Alper, Phil; Betschart, Claudia; André, Cédric; Boulay, Thomas; Cheng, Dai; Deane, Jonathan; Faller, Michael; Feifel, Roland; Glatthar, Ralf; Han, Dong; Hemmig, Rene; Jiang, Tao; Knoepfel, Thomas; Maginnis, Jillian; Mutnick, Daniel; Pei, Wei; Ruzzante, Giulia; Syka, Peter; Zhang, Guobao; Zhang, Yi; Zink, Florence; Zipfel, Géraldine; Hawtin, Stuart; Junt, Tobias; Michellys, Pierre-Yves.
Affiliation
  • Alper P; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Betschart C; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • André C; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Boulay T; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Cheng D; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Deane J; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Faller M; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Feifel R; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Glatthar R; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Han D; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Hemmig R; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Jiang T; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Knoepfel T; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Maginnis J; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Mutnick D; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Pei W; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Ruzzante G; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Syka P; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Zhang G; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Zhang Y; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
  • Zink F; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Zipfel G; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Hawtin S; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Junt T; Novartis Institutes for Biomedical Research, Fabrikstrasse 2, Novartis Campus, CH-4056 Basel, Switzerland.
  • Michellys PY; Novartis Institutes for Biomedical Research, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
ACS Med Chem Lett ; 14(8): 1054-1062, 2023 Aug 10.
Article in En | MEDLINE | ID: mdl-37583811
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Full text: 1 Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2023 Type: Article Affiliation country: United States