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Carriers of rare damaging CCR2 genetic variants are at lower risk of atherosclerotic disease.
Georgakis, Marios K; Malik, Rainer; Hasbani, Natalie R; Shakt, Gabrielle; Morrison, Alanna C; Tsao, Noah L; Judy, Renae; Mitchell, Braxton D; Xu, Huichun; Montasser, May E; Do, Ron; Kenny, Eimear E; Loos, Ruth J F; Terry, James G; Carr, John Jeffrey; Bis, Joshua C; Psaty, Bruce M; Longstreth, W T; Young, Kendra A; Lutz, Sharon M; Cho, Michael H; Broome, Jai; Khan, Alyna T; Wang, Fei Fei; Heard-Costa, Nancy; Seshadri, Sudha; Vasan, Ramachandran S; Palmer, Nicholette D; Freedman, Barry I; Bowden, Donald W; Yanek, Lisa R; Kral, Brian G; Becker, Lewis C; Peyser, Patricia A; Bielak, Lawrence F; Ammous, Farah; Carson, April P; Hall, Michael E; Raffield, Laura M; Rich, Stephen S; Post, Wendy S; Tracy, Russel P; Taylor, Kent D; Guo, Xiuqing; Mahaney, Michael C; Curran, Joanne E; Blangero, John; Clarke, Shoa L; Haessler, Jeffrey W; Hu, Yao.
Affiliation
  • Georgakis MK; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany.
  • Malik R; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hasbani NR; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Shakt G; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany.
  • Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Tsao NL; Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Judy R; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Mitchell BD; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Xu H; Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Montasser ME; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Do R; Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Kenny EE; Corporal Michael Crescenz VA Medical Center, Philadelphia, PA, USA.
  • Loos RJF; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
  • Terry JG; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD.
  • Carr JJ; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
  • Bis JC; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
  • Psaty BM; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Longstreth WT; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Young KA; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lutz SM; The Center for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Cho MH; Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Broome J; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Khan AT; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Wang FF; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Heard-Costa N; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Seshadri S; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Vasan RS; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Palmer ND; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA.
  • Freedman BI; Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Bowden DW; Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Yanek LR; Department of Neurology, University of Washington, Seattle, WA, USA.
  • Kral BG; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora CO, USA.
  • Becker LC; Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA, USA.
  • Peyser PA; Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
  • Bielak LF; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Ammous F; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Carson AP; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Hall ME; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Raffield LM; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Rich SS; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
  • Post WS; Bigg's Institute for Alzheimer's Disease and neurodegenerative disorders, University of Texas Health Science Center, San Antonio, TX, USA.
  • Tracy RP; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Taylor KD; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
  • Guo X; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
  • Mahaney MC; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Curran JE; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Blangero J; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • Clarke SL; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Haessler JW; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Hu Y; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
medRxiv ; 2023 Aug 16.
Article in En | MEDLINE | ID: mdl-37645892
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Full text: 1 Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: MedRxiv Year: 2023 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: MedRxiv Year: 2023 Type: Article Affiliation country: Germany