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Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis.
Mukherjee, Abir; Bezwada, Divya; Greco, Francesco; Zandbergen, Malu; Shen, Tong; Chiang, Chun-Yi; Tasdemir, Medine; Fahrmann, Johannes; Grapov, Dmitry; La Frano, Michael R; Vu, Hieu S; Faubert, Brandon; Newman, John W; McDonnell, Liam A; Nezi, Luigi; Fiehn, Oliver; DeBerardinis, Ralph J; Lengyel, Ernst.
Affiliation
  • Mukherjee A; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology-Center for Integrative Sciences, University of Chicago, Chicago, IL, USA.
  • Bezwada D; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Greco F; Fondazione Pisana per la Scienza ONLUS, San Giuliano Terme, Italy.
  • Zandbergen M; Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
  • Shen T; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology-Center for Integrative Sciences, University of Chicago, Chicago, IL, USA.
  • Chiang CY; NIH West Coast Metabolomics Center, University of California, Davis, CA, USA.
  • Tasdemir M; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology-Center for Integrative Sciences, University of Chicago, Chicago, IL, USA.
  • Fahrmann J; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology-Center for Integrative Sciences, University of Chicago, Chicago, IL, USA.
  • Grapov D; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • La Frano MR; NIH West Coast Metabolomics Center, University of California, Davis, CA, USA.
  • Vu HS; NIH West Coast Metabolomics Center, University of California, Davis, CA, USA.
  • Faubert B; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Newman JW; Department of Medicine/Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • McDonnell LA; NIH West Coast Metabolomics Center, University of California, Davis, CA, USA.
  • Nezi L; Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
  • Fiehn O; Department of Experimental Oncology, IRCCS European Institute of Oncology, Milano, Italy.
  • DeBerardinis RJ; NIH West Coast Metabolomics Center, University of California, Davis, CA, USA.
  • Lengyel E; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Nat Metab ; 5(9): 1563-1577, 2023 09.
Article in En | MEDLINE | ID: mdl-37653041
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Glycerol Limits: Female / Humans Language: En Journal: Nat Metab Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Glycerol Limits: Female / Humans Language: En Journal: Nat Metab Year: 2023 Type: Article Affiliation country: United States