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Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43.
Tanaka, Yoshinori; Ito, Shun-Ichi; Honma, Yuki; Hasegawa, Masato; Kametani, Fuyuki; Suzuki, Genjiro; Kozuma, Lina; Takeya, Kosuke; Eto, Masumi.
Affiliation
  • Tanaka Y; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan. Electronic address: y-tanaka@ous.ac.jp.
  • Ito SI; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan.
  • Honma Y; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan.
  • Hasegawa M; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
  • Kametani F; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
  • Suzuki G; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
  • Kozuma L; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan.
  • Takeya K; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan.
  • Eto M; Biochemistry Unit, Faculty of Veterinary Medicine, Okayama University of Science, Imabari-shi, Ehime, Japan.
J Biol Chem ; 299(11): 105272, 2023 11.
Article in En | MEDLINE | ID: mdl-37739033
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Full text: 1 Database: MEDLINE Main subject: Autophagy / DNA-Binding Proteins / Progranulins / Lysosomes Limits: Humans Language: En Journal: J Biol Chem Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Autophagy / DNA-Binding Proteins / Progranulins / Lysosomes Limits: Humans Language: En Journal: J Biol Chem Year: 2023 Type: Article